Med. praxi. 2021;18(4):256-260 | DOI: 10.36290/med.2021.043

Gastroesophageal reflux disease: current state of the issue

MUDr. Eva Mayerová

II. interní klinika FN Plzeň

Gastroesophageal reflux disease is a frequent gastrointestinal disease characterized by a broad spectrum of symptoms, ranging from mild irregular complaints to the presence of serious Barrett's esophagus. In addition to typical symptoms, i.e., pyrosis and regurgitation, there can be a number of atypical and extraesophageal symptoms. Proton pump inhibitors still play a major role in pharmacotherapy. In the past decade, significant advances were made in endoscopic treatment methods which are particularly used in the management of complications. In the majority of cases, the course of the disease is prolonged requiring long-term maintenance treatment. A surgical antireflux procedure is considered when the efficacy of conservative treatment is insufficient.

Keywords: gastroesophageal reflux disease, typical symptoms, extraesophageal symptoms, Barrett's esophagus, proton pump inhibitors, fundoplication.

Published: September 17, 2021  Show citation