Med. Pro Praxi 2009; 6(6): 304-307

Macrolides for practice

prof. MUDr. Jiří Havlík DrSc1,2
1 Emeritní profesor I. infekční kliniky 2. LF UK, FN Na Bulovce, Praha
2 I. infekční klinika 2. LF a Katedra infekčních nemocí IPVZ, Praha

Macrolide antibiotics are effective against numerous gram+ and gram- microbes as well as against chlamydia and mycoplasms, the most

common agents causing respiratory and urinary tract infections. Daily doses are relatively low, administered at longer intervals, and

well tolerated by both children and adults. Their action is bacteriostatic; therefore, they are suitable for mild to moderate infections.

As mostly administered orally, macrolide antibiotics are only second to beta-lactam antibiotics as the most commonly prescribed antiinfective

agents in ambulatory practice.

Keywords: natural macrolides, semisynthetic macrolides, azalides, ketolides.

Published: January 1, 2010  Show citation

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Havlík J. Macrolides for practice. Med. praxi. 2009;6(6):304-307.
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    References

    1. Příborský J. Makrolidy. Praha: Maxdorf, 2001: 1-107 s.
    2. Bryskier A, Butzler J-P. Macrolides. In: FinchRG, Greenwood D, Norrby SR, Whitley RS. Antibiotic and Chemotherapy. 8th ed. Churchill Livingstone, 2003: 310-325.
    3. Havlík J. Makrolidová antibiotika v pediatrické praxi. Pediatrie pro praxi 2009; 10(2): 76-79.
    4. Urbášková P, Marešová V, Jindrák V, et al. Koncenzus používání antibiotik: II. Makrolidová antibiotika. Practicus 2004; 3(2): 28-34.
    5. Sechser T, Filipová H. Klinická farmakologie makrolidových antibiotik. Causa Subita 2001; 4(1): 44-46.
    6. Jindrák V, Henišová J, Vaniš V, et al. Rezistence Streptococcus pyogenes k erytromycinu jako regionální problém. KMIL 1999: 5: 237-243.
    7. Havlík J. Makrolidová antibiotika - minulost, přítomnost i budoucnost. KMIL 1999; 7: 216-227.

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