Med. praxi. 2014;11(4):150-154
Allergic rhinitis
- Ústav imunologie a mikrobiologie 1. LF UK a VFN, Praha
Beginning of pollen season brings us each year an increasing amount of patients suffering from allergic rhinoconjunctivitis. It has been
estimated that in Czech Republic 2.5 millions people suffer from any kind of allergic disease and about 15 % suffer from allergic rhinitis.
Etiopathogenesis of allergic rhinitis is based on IgE – mediated response of organism onto frequent contact with an allergen. Eosinophilic
inflammation is then the final result of this activation and leads to clinical symptoms as a runny nose, obturation, sneezing and fatigue.
Suppression of the inflammation is the first-line task. Symptomatic therapy represents mostly using of antihistamines in systemic and local
application and nasal corticosteroids. In indicating cases we use specific allergen immunotherapy which is potentially a causal therapy.
Keywords: allergic rhinitis, eosinophilic inflammation, antihistamines, nasal corticosteroids, allergen immunotherapy
Published: June 1, 2014 Show citation
References
- Blaiss MS. Cognitive, social and economic costs of allergic rhinitis. Allergy Astma Proc 2000; 21: 7-13.
Go to original source... 
Go to PubMed... - Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Astma (ARIA) 2008 update (in collaboration with the Health Organization, GA (2)LEN and Alergen). Allergy 2008; Suppl 86/63: 8-160Adelsberg J, Philips G, Pedinoff EO et al. Montelukast improves symptom sof seasonal allergic rhinitis over 4-week treatment period. Allergy 2003; 58: 1268-1276. Go to original source... Go to PubMed...
- Jaeger S. Exposure to grass pollen in Europe. Clin Exo Allergy Rev 2008; 8: 2-6. Go to original source...
- Cauwenberge P, et al. Konsensus statement on the treatment of allergic rhinitis. European Academy of Alergology and Clinical Imunology, Allergy; 55(2): 116-134.
- Špičák V, Rybníček O, Fuchs M, Kučera P. Alergeny. In: Špičák V a kol. Alergologie. Galén Praha 2004: 55-80.
- Barney NP, Grazino FM. Allergic and immunological diseases of the eye. In Middleton's Allergy: Principles and Praktice. Philadelphia (PA): Mosby, 2009. Go to original source...
- Crockard AD, Ennis M. Laboratory-based allergy diagnosis: should we go with the flow? Clin Exp Allergy 2001; 31: 975-977. Go to original source... Go to PubMed...
- Fučíková T, Humlová Z. Laboratorní diagnostika v imunologii. In: Zima T a kol Laboratorní diagnostika. Třetí, doplněné a přepracované vydání. Galén a Karolinum Praha 2013: 735-743.
- Honzová S, Havranová M. Test aktivace bazofilů, jeho přínos pro klinickou praxi. Alergie 2003; 4: 292-297.
- Petrů V. Obecné zásady léčby. In: Špičák V, a kol. Alergologie. Galén Praha 2004: 127-129.
- Simons FE. H1-antihistamines: A more relevant than ever in the treatment of allergic disorders. J Allergy Clin Immunol 2003; 112(4): 42-52. Go to original source... Go to PubMed...
- Mygind N, Nielsen LP, Hoffman HJ, et al. Mode of action of intranasal corticosteroids. J Allergy Clin Immunol 2001; 108(Suppl.1): S16-S25. Go to original source... Go to PubMed...
- Barroody FM, Foster KA, Markaryan A, et al. Nasal ocular reflexes and eye symptoms in patiens with allergic rhinitis. Ann Allergy Astma Immunol 2008; 100: 194-199. Go to original source... Go to PubMed...
- Adelsberg J, Philips G, Pedinoff EO, et al. Montelukast improves symptom sof seasonal allergic rhinitis over 4-week treatment period. Allergy 2003; 58: 1268-1276. Go to original source... Go to PubMed...