Med. praxi. 2015;12(3):106-108

Medical treatment for chronic heart failure

MUDr.Gabriela Štěrbáková, Ph.D.
Kardiologické oddělení FN a LF UK Plzeň

Heart failure is a frequent disease with a serious morbidity and mortality. The article summarizes new recommendations for pharmacological

therapy for chronic heart failure. The mainstay of treatment is to interfere with neurohumoral activation that plays a crucial role

in the pathophysiology of heart failure, in particular with beta blockers and ACE inhibitors; in the case of persistent symptomatology

with mineralocorticoid receptor blockers. The results of studies of the angiotensin receptor neprilysin inhibitor appear promising. The

recommendations newly include ivabradine.

Keywords: chronic heart failure, pharmacotherapy, neurohumoral activation interference, ivabradine

Published: June 24, 2015  Show citation

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Štěrbáková G. Medical treatment for chronic heart failure. Med. praxi. 2015;12(3):106-108.
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    References

    1. Špinar J, Vítovec J, Hradec J, Málek I, Meluzín J, Špinarová L, Hošková L, Hegarová M, Ludka O, Táborský M. Czech Society of Cardiology guidelines for the diagnosis and treatment of chronic heart failure 2011. Cor et Vasa 2012; 54: e114-e1341. Go to original source...
    2. McMurray JJ, Adamopoulos S, Anker SD, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 2012; 33: 1787-1847. Go to PubMed...
    3. McMurray JJ, Hradec J, Vítovec J, Špinar J. Doporučený postup Evropské kardiologické společnosti pro diagnostiku a léčbu akutního a chronického srdečního selhání - 2012. Souhrn dokumentu připravený Českou kardiologickou společností. Cor Vasa.
    4. Vítovec J, Špinar J. Co v oblasti srdečního selhávání přinesla nová doporučení ČKS a ESC? Interní medicína 2013; 15 (10): 289-291.
    5. Jaromír Hradec, Jiří Vítovec, Jindřich Špinar. Nová doporučení pro diagnostiku a léčbě srdečního selhání. Kapitoly z kardiologie propraktické lékaře 2012;4:136-143.
    6. Špinar J, Vítovec J, Hradec J, et al. Czech Society of Cardiology guidelines for the diagnosis and treatment of chronic heart failure. Cor Vasa 2012; 54: e113-e134. Go to original source...
    7. Jaromír Hradec, Jiří Vítovec, Jindřich Špinar. Nová doporučení pro diagnostiku a léčbě srdečního selhání. Kapitoly z kardiologie propraktické lékaře 2012; 4: 136-143.

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