Med. praxi. 2017;14(4):177-179 | DOI: 10.36290/med.2017.033

Peptic ulcer disease

MUDr. Michal Konečný, Ph.D.
II. interní klinika – gastroenterologická a hepatologická, Fakultní nemocnice Olomouc

The incidence of peptic ulcers in areas of natural resistance to aggressive constituents of digestive juices is called gastroduodenalulcer disease. After the discovery of the main etiological factors, Helicobacter pylori infection and the overuse of nonsteroidalanti-inflammatory drugs, the introduction of advanced endoscopic diagnostic methods and proton pump inhibitors into clinicalpractice dramatically improved the prognosis of patients with gastroduodenal ulcer disease and significantly reduced the recurrencerate. The most serious complications include bleeding and perforation of the ulcer, serious adverse events of which themorbidity and mortality have been reduced only slightly, and in recent decades have not changed significantly.

Keywords: peptic ulcer disease, Helicobacter pylori, endoscopy, proton pumps inhibitors

Published: November 1, 2017  Show citation

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Konečný M. Peptic ulcer disease. Med. praxi. 2017;14(4):177-179. doi: 10.36290/med.2017.033.
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