Med. praxi. 2020;17(4):269-271 | DOI: 10.36290/med.2020.051

Biological treatment today - a brief overview for general practitioners

Mgr. ©árka Sperottová1,2, MUDr. Petra Matalová, Ph.D.1
1 Ústav farmakologie LF UP a FN Olomouc
2 Lékárna FN Olomouc

Target therapy is a rapidly evolving class of drugs. Thanks to their advantages, such as selectivity, they have found a firm place in modern medicine and other substances are constantly appearing on the market. They are usually polypeptides or proteins with a not exactly defined structure. Some "generics" of original medicines, so-called biosimilars, are marketable.

Keywords: target therapy, monoclonal antibodies.

Published: September 25, 2020  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Sperottová ©, Matalová P. Biological treatment today - a brief overview for general practitioners. Med. praxi. 2020;17(4):269-271. doi: 10.36290/med.2020.051.
Download citation

References

  1. Pavelka K, Arenberger P, a kol. Biologická léčba zánětlivých onemocnění. Grada 2014.
  2. Vetchý D, Vetchá M. Biosimilars - podobné biologické léčivé přípravky. Remedia 2010; 20: 74-77.
  3. Shepard HM, Phillips GL, D Thanos C, Feldmann M. Developments in therapy with monoclonal antibodies and related proteins. Clin Med (Lond). 2017 Jun; 17(3): 220-232. Go to original source...
  4. Hansel TT, Kropshofer H, Singer T, Mitchell JA, George AJ. The safety and side effects of monoclonal antibodies. Nat Rev Drug Discov. 2010 Apr; 9(4): 325-338. Go to original source... Go to PubMed...
  5. Serra López-Matencio JM, Martínez Nieto C, Morell Baladrón A, Castañeda S. Drug Interactions Of Monoclonal Antibodies-Clinical Perspective. J Immunol Sci. 2018; 2(2): 4-7. Go to original source...
  6. Matalová P. Vybraná biologická léčiva v neonkologických indikacích. Klin Farmakol Farm 2018; 32(3): 19-25. Go to original source...
  7. Databáze léků SÚKL. ČR 2020. Dostupné z: http://www.sukl.cz/modules/medication/search.php
  8. Linkos. Slovníček. 2020 ČOS ČLS JEP [online]. Dostupné z: https://www.linkos.cz/slovnicek/cilena-lecba/




Medicine for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.