Med. praxi. 2024;21(5):306-313 | DOI: 10.36290/med.2024.033

Critical evaluation of intravenous vitamin C in practice

PharmDr. Marek Lapka, Ph.D.
Ústav farmakologie 3. LF UK, Praha

Vitamin C is important as a reducing agent and is involved in many biological processes, including collagen and neurotransmitter synthesis. This study aimed to critically review the available information on the potential of intravenous vitamin C (IVC) in oncology and to discuss cases where its use might be indicated. A literature review of available scientific publications focusing on the use of IVC in the treatment of cancer was conducted. Papers from the last two decades were included, including phase I-III trials that evaluated the safety, tolerability, and efficacy of IVC. High-dose IVC has potential as an adjuvant therapy in oncology, particularly in combination with chemotherapy and radiotherapy. However, further large-scale trials are needed to confirm these findings and to define optimal dosages and schedules in specific indications.

Keywords: vitamin C, ascorbic acid, high dose, oncology, cancer.

Received: July 19, 2024; Revised: August 28, 2024; Accepted: September 4, 2024; Published: December 2, 2024  Show citation

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Lapka M. Critical evaluation of intravenous vitamin C in practice. Med. praxi. 2024;21(5):306-313. doi: 10.36290/med.2024.033.
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