Med. praxi. 2025;22(2):98-103 | DOI: 10.36290/med.2025.020

Acute and recurrent pericarditis - what a general practitioner should know

MUDr. Sabrina Adamíková, prof. MUDr. Jan Krejčí, Ph.D.
I. interní kardioangiologická klinika Fakultní nemocnice u sv. Anny v Brně

Pericarditis is the most common pathological process affecting the pericardium. The diagnosis is based on the fulfillment of two of the four classification criteria. Acute pericarditis may be associated with infectious, systemic, or autoimmune diseases, as well as malignancies or metabolic disorders. The basis of the diagnosis of acute pericarditis is an echocardiographic examination, which can help to exclude other acute cardiac conditions. The most common form in developed countries is idiopathic or post-viral pericarditis, the treatment of which is based on the administration of nonsteroidal anti-inflammatory drugs and colchicine. Corticosteroids are the second line of treatment, and their biggest pitfall is the increased risk of recurrent pericarditis, which occurs in up to 30 % of cases.

Keywords: pericarditis, friction rub, echocardiography, colchicine, nonsteroidal anti­‑inflammatory drugs, corticosteroids.

Received: November 1, 2024; Accepted: March 31, 2025; Published: April 30, 2025  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Adamíková S, Krejčí J. Acute and recurrent pericarditis - what a general practitioner should know. Med. praxi. 2025;22(2):98-103. doi: 10.36290/med.2025.020.
Download citation

References

  1. Adler Y, Charron P, Imazio M, et al; ESC Scientific Document Group. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC)Endorsed by: The European Association for Cardio­‑Thoracic Surgery (EACTS). Eur Heart J. 2015 Nov 7;36(42):2921-2964. doi: 10.1093/eurheartj/ehv318. Epub 2015 Aug 29. PMID: 26320112; PMCID: PMC7539677. Go to original source... Go to PubMed...
  2. Táborský M, Kautzner J, Linhart A, et al. Kardiologie. Praha: EEZY Publishing; 2024.
  3. Dababneh E, Siddique MS. Pericarditis. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
  4. Chiabrando JG, Bonaventura A, Vecchié A, et al. Management of Acute and Recurrent Pericarditis: JACC State­‑of­‑the­‑Art Review. J Am Coll Cardiol. 2020 Jan 7;75(1):76-92. doi: 10.1016/j.jacc.2019. 11. 021. PMID: 31918837. Go to original source...
  5. Linhart A, Tousek P. Summary of 2015 ESC Guidelines for the diagnosis and management of pericardial diseases. Prepared by the Czech Society of Cardiology. Cor et Vasa. 2016;58:e106-e126. Go to original source...
  6. Imazio M, Adler Y. Management of pericardial effusion. Eur Heart J. 2013 Apr;34(16):1186-97. doi: 10.1093/eurheartj/ehs372. Epub 2012 Nov 2. PMID: 23125278. Go to original source... Go to PubMed...
  7. Sagristà­‑Sauleda J, Mercé AS, Soler­‑Soler J. Diagnosis and management of pericardial effusion. World J Cardiol. 2011 May 26;3(5):135-43. doi: 10.4330/wjc.v3.i5.135. PMID: 21666814; PMCID: PMC3110902. Go to original source... Go to PubMed...
  8. Lhotský J, Hromádka M, Pechman V, et al. Akutní perikarditida. Interv Akut Kardiol. 2019;18(2):105-108. Go to original source...
  9. Imazio M. Medical therapy of pericarditis: tips and tricks for clinical practice. J Cardiovasc Med (Hagerstown). 2024 Jun 1;25(6):420-425. doi: 10.2459/JCM.0000000000001618. Epub 2024 Apr 1. PMID: 38625826; PMCID: PMC11216374. Go to original source... Go to PubMed...
  10. Imazio M, Bobbio M, Cecchi E, et al. Colchicine in addition to conventional therapy for acute pericarditis: results of the COlchicine for acute PEricarditis (COPE) trial. Circulation. 2005 Sep 27;112(13):2012-6. doi: 10.1161/CIRCULATIONAHA.105.542738. PMID: 16186437. Go to original source... Go to PubMed...
  11. Imazio M, Brucato A, Cemin R, et al; ICAP Investigators. A randomized trial of colchicine for acute pericarditis. N Engl J Med. 2013 Oct 17;369(16):1522-8. doi: 10.1056/NEJMoa1208536. Epub 2013 Aug 31. PMID: 23992557. Go to original source... Go to PubMed...
  12. Principi N, Lazzara A, Paglialonga L, et al. Recurrent pericarditis and interleukin (IL)-1 inhibitors. Int Immunopharmacol. 2024 Nov 15;141:113017. doi: 10.1016/j.intimp.2024.113017. Epub 2024 Aug 27. PMID: 39197293. Go to original source... Go to PubMed...
  13. Brucato A, Imazio M, Gattorno M, et al. Effect of Anakinra on Recurrent Pericarditis Among Patients With Colchicine Resistance and Corticosteroid Dependence: The AIRTRIP Randomized Clinical Trial. JAMA. 2016 Nov 8;316(18):1906-1912. doi: 10.1001/jama.2016.15826. PMID: 27825009. Go to original source... Go to PubMed...




Medicine for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.