Med. praxi. 2025;22(3):225-226

Nutraceuticals and their use in the clinical practice of the general practitioner

doc. MUDr. Dalibor Pastucha, Ph.D., MBA1, 2, Ing. Hana Střítecká, Ph.D.3, 4
1 Obezitologická ambulance, ReFit Clinic, s. r. o, Olomouc
2 Klinika rehabilitace a tělovýchovného lékařství, FN Ostrava a LF Ostravská univerzita
3 Ústav preventivního lékařství, Lékařská fakulta UK v Hradci Králové
4 CASRI - Vědecké a servisní pracoviště tělesné výchovy a sportu, Praha

Nutraceuticals are natural substances and dietary supplements with potential health benefits, disease prevention, and metabolic balance optimization. While their use is increasing, there is no definition, and regulations across the EU focus primarily on safety. Their recommendation should be evidence-based, as they can interact with medications and affect treatment outcomes. Examples of proven efficacy include vitamin D and lipid-lowering supplements like phytosterols or red yeast rice extract containing monacolin K. It's essential to choose verified products and consult healthcare professionals to avoid adverse effects or improper use. Nutraceuticals should not replace conventional medicine but can serve as supplementary agents within a safe and informed framework.

Keywords: nutraceuticals, dietary supplements, general practitioner.

Published: June 26, 2025  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Pastucha D, Střítecká H. Nutraceuticals and their use in the clinical practice of the general practitioner. Med. praxi. 2025;22(3):225-226.
Download citation
PDF will be unlocked 26.6.2026

References

  1. . Campbell WW, et al. Nutraceuticals: a new paradigm for health maintenance and disease prevention. Journal of Clinical Nutrition. 2004;78(4):658-661.
  2. . Coppens P, da Silva MF, Pettman S. European regulations on nutraceuticals, dietary supplements and functional foods: a framework based on safety. Toxicology. 2006 Apr 3;221(1):59-74. doi: 10.1016/j.tox.2005.12.022. Epub 2006 Feb 15. PMID: 16469424. Go to original source... Go to PubMed...
  3. . Nařízení Evropského parlamentu a Rady (EU) č. 2015/2283.
  4. . Nařízení Evropského parlamentu a Rady (EU) č. 1169/2011.
  5. . Regulation (EC) No 1924/2006 on nutrition and health claims made on foods.
  6. . Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017 Feb 15;356:i6583. doi: 10.1136/bmj.i6583. PMID: 28202713; PMCID: PMC5310969. Go to original source... Go to PubMed...
  7. . Nařízení Evropského parlamentu a Rady (EU) č. 2015/2283.
  8. . Cicero AFG, Kennedy C, Knežević T, et al. Efficacy and Safety of Armolipid Plus®: An Updated PRISMA Compliant Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials. Nutrients. 2021 Feb 16;13(2):638. doi: 10.3390/nu13020638. PMID: 33669333; PMCID: PMC7920267. Go to original source... Go to PubMed...
  9. . Vrablík M, Piťha J, Bláha V, et al. Stanovisko výboru České společnosti pro aterosklerózu k doporučením ESC/EAS pro diagnostiku a léčbu dyslipidemií z roku 2019. Vnitřní lékařství. 2019;65(12):743-754. Go to original source...
  10. . Mach F, Baigent C, Catapano AL, et al. ESC Scientifi c Document Group. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modifi cation to reduce cardiovascular risk. Eur Heart J. 2020;41:111-188 Go to original source... Go to PubMed...
  11. . Penson PE, Banach M. Natural compounds as anti-atherogenic agents: Clinical evidence for improved cardiovascular outcomes. Atherosclerosis. 2021;316:58-65. doi: 10.1016/j.atherosclerosis.2020.11.015. Go to original source... Go to PubMed...




Medicine for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.