Med. praxi. 2010;7(4):161-162

Perioperative bridging of peroral anticoagulant therapy in patients requiring surgery

doc.MUDr.Věra Krčová, CSc., MUDr.Antonín Hluší

Hemato-onkologická klinika LF UP a FN Olomouc

Patients receiving chronic anticoagulation therapy posse a clinical challenge when therapy needs to be interrupted for surgical or invasive

procedures. The management of warfarin therapy in patients undergoing surgery or other risk of hemorrhage needs to evaluate risk

of thrombotic or hemorrhagic complications. Procedures with the low risk of hemorrhage can be provided with continuing of anticoagulation

therapy. In the other hand, surgery with high risk of haemorrhage need stopping warfarin and starting bridging anticoagulant therapy

with unfractionated heparin or mostly in our conditions with low molecular heparin prior and after surgery. Periprocedural treatment of

patients undergoing long-term anticoagulant therapy requires a competent evaluation of individualized risks versus benefits.

Keywords: anticoagulant therapy, warfarin, invasive procedures, bridging therapy

Published: May 1, 2010  Show citation