Med. praxi. 2010;7(4):167-172

Rational diagnostics and treatment of diseases of the thyroid gland

MUDr.Jan Jiskra, Ph.D.
3. interní klinika VFN a 1. LF UK, Praha
Tyreopatie patří mezi nemoci masového výskytu a neléčené přinášejí postiženým významná zdravotní rizika. Na druhou stranu i nesprávně

Thyroid disorders are common diseases and, when untreated, are associated with significant health risks. On the contrary non-reasoned

treatment and levothyroxine overdose may have negative consequences, especially in the elderly. Correct diagnosis including

determination of etiology is always the precondition for effective treatment. The treatment is always individual with respect to age and

other circumstances and the patients should be followed up. Levothyroxine overtreatment should be avoided and subclinical hyperthyroidism

should be more frequently treated in patients over 80 years.

Keywords: hypothyroidism, hyperthyroidism, thyroid stimulating hormone, thyroid peroxidase antibodies, thyroid ultrasound

Published: May 1, 2010  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Jiskra J. Rational diagnostics and treatment of diseases of the thyroid gland. Med. praxi. 2010;7(4):167-172.
Download citation

References

  1. Zamrazil V. Jodový deficit, jeho význam a způsoby řešení. In: Stárka, et al. Aktuální endokrinologie. Praha: Maxdorf-Jessenius, 1999: 366-391.
  2. Jiskra J, Límanová Z, Potluková E, et al. Význam screeningu tyreopatií u těhotných žen: patofyziologický podklad a praktické aspekty. Cas Lek Cesk 2007; 146: 827-833. Go to PubMed...
  3. Jiskra J, Límanová Z, Vanícková Z, et al. IgA and IgG antigliadin, IgA anti-tissue transglutaminase and antiendomysial antibodies in patients with autoimmune thyroid diseases and their relationship to thyroidal replacement therapy. Physiol Res 2003; 52: 79-88. Go to original source...
  4. Abalovich M, Nobuyuki A, Barbour LA, et al. Clinical Practice Guideline. Management of thyroid dysfunction during pregnancy and postpartum: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2007; 92: S1-47. Go to original source... Go to PubMed...
  5. Parle JV, Maisonneuve P, Sheppard MC, et al. Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study. Lancet 2001; 358: 861-865. Go to original source... Go to PubMed...
  6. Cappola AR, Fried LP, Arnold AM, et al. Thyroid status, cardiovascular risk, and mortality in older adults. JAMA 2006; 295: 1033-1041. Go to original source... Go to PubMed...
  7. Ochs N, Auer R, Bauer DC, et al. Meta-analysis: subclinical thyroid dysfunction and he risk for coronary heart disease and mortality. Ann Intern Med 2008; 148: 832-845. Go to original source... Go to PubMed...
  8. Goichot B, Sapin R, Schlienger JL. Subclinical hyperthyroidism: considerations in defining the lower limit of the thyrotropin reference interval. Clin Chem 2009; 55: 420-424. Go to original source... Go to PubMed...
  9. Vanderpump MP. How should we manage patients with mildly increased serum thyrotrophin concentrations? Clin Endocrinol (Oxf) 2009; Sep 24 [Epub ahead of print].
  10. Razvi S, Shakoor A, Vanderpump M, et al. The influence of age on the relationship between subclinical hypothyroidism and ischemic heart disease: a metaanalysis. J Clin Endocrinol Metab 2008; 93: 2998-3007. Go to original source... Go to PubMed...
  11. Iacoviello M, Guida P, Guastamacchia E, et al. Prognostic role of sub-clinical hypothyroidism in chronic heart failure outpatients. Curr Pharm Des 2008; 14: 2686-2692. Go to original source... Go to PubMed...
  12. Cooper DS. Approach to the patient with subclinical hyperthyroidism. J Clin Endocrinol Metab 2007; 92: 3-9. Go to original source... Go to PubMed...




Medicine for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.