Med. praxi. 2021;18(1):68-70 | DOI: 10.36290/med.2021.011

Whipple's disease

MUDr. Daniel Bakši
II. interní oddělení - Gastroenterologie, Krajská zdravotní, a. s., Nemocnice Teplice, o. z.

Whipple's disease is a rare systemic disease of infectious etiology caused by the bacterium Tropheryma whipplei. Typical symptoms of this disease are chronic diarrhea, abdominalgia, weight loss, polyarthralgia and fever. In our case report, we present a 52 - year old patient, who was sent by a general practitioner for examination at our department for significant weight loss, weakness and prolonged lower dyspeptic syndrome. Gastroscopy with biopsy from the duodenal mucosa helped us to diagnose Whipple's disease, which led to the early initiation of targeted therapy, which is based mainly on long-term antibiotic treatment.

Keywords: Whipple's disease, Tropheryma whipplei, weight loss, diarrhea.

Published: April 6, 2021  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Bakši D. Whipple's disease. Med. praxi. 2021;18(1):68-70. doi: 10.36290/med.2021.011.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Kojecký Z, Benýšek L, Krč I, Ehrmann J, Koďousek R, Malinský J. Reminiscence k stoletému výročí objevu Whippleovy nemoci: souborný referát. Vnitř Lék 2008; 54(3): 287-304. Go to PubMed...
    2. Puéchal X. Whipple's disease. Annals of the Rheumatic Diseases 2013; 72: 797-803. Go to original source... Go to PubMed...
    3. Klener P, et al. Vnitřní lékařství. Praha: Galén, 2006: 594-0595.
    4. Schneider T, Moos V. Tropheryma whipplei: pathogen of Whipple's disease and more. Dtsch Med Wochenschr. 2015; 140(6): 428-432. Go to original source... Go to PubMed...
    5. Marth T, Raoult D. Whipple's disease. The Lancet 2003; 361(9353): 239-246. Go to original source... Go to PubMed...
    6. El-Abassi R, Soliman MY, Williams F, England JD. Whipple's disease. Journal of the Neurological Sciences 2017; 377: 197-206. Go to original source... Go to PubMed...
    7. Obst W, von Arnim U, Malfertheiner P. Whipple's Disease. Viszeralmedizin 2014; 30(3): 167-172. Go to original source... Go to PubMed...
    8. De Francesco V, Corsi F, et al. Whipple's disease: case report and review of the literature. J Gastrointestin Liver Dis. 2018; 27(3): 331-336. Go to original source... Go to PubMed...

    Return to the content


    Medicine for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.