Med. praxi. 2026;23(2):101-105 | DOI: 10.36290/med.2026.001

Primary prevention of frailty syndrome

PhDr. Iveta Ondriová, PhD.
Katedra ošetrovateľstva, Fakulta zdravotníckych odborov PU v Prešove

Frailty syndrome is a complex geriatric syndrome characterized by a significant loss of functional reserves, compensatory and adaptive mechanisms and increased vulnerability to external or internal stressors. Frailty syndrome in the narrow sense primarily includes significant and unintentional weight loss, reduction of muscle mass, which is associated with slowed gait, feeling of fatigue or faster fatigue, cognitive functions are also impaired, depression, loss of motivation, sleep disorders occur. The condition is accentuated by sensory disorders. Frailty is the most problematic manifestation of population aging.

Keywords: senior, frailty syndrome, manifestations, prevention.

Received: July 30, 2025; Revised: December 15, 2025; Accepted: January 3, 2026; Published: April 28, 2026  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Ondriová I. Primary prevention of frailty syndrome. Med. praxi. 2026;23(2):101-105. doi: 10.36290/med.2026.001.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Purchase PDF - 60 CZK (2.5 EUR)
    will be unlocked 28.4.2027

    References

    1. Veronese N, Custodero C, Cella A, et al. Prevalence of multidimensional frailty and pre-frailty in older people in different settings: A systematic review and meta-analysis. Ageing Res Rev. 2021 Dec;72:101498. doi: 10.1016/j.arr.2021.101498. Epub 2021 Oct 23. PMID: 34700009; PMCID: PMC12149324. Go to original source... Go to PubMed...
    2. Hudáková A, Novotná Z, Németh F, et al. Geriatrické syndrómy ako prediktory ošetrovateľstva v geriatrii. Prešov: Prešovská univerzita v Prešove; 2016.
    3. Hegyi L, Krajčík Š. Geriatria pre praktického lekára. 3. vyd. Bratislava: Herba; 2015.
    4. Abdelhamid A, Jennigs A, Hayhoe RPG, Awuzudike VE, et al. High variability of food and nutrient intake exists across the Mediterranean Dietary Pattern - A systematic review. Food Sci. Nutr. 2020;8:4907-4918. doi: 10.1002/fsn3.1784. Go to original source... Go to PubMed...
    5. Bodáková D. Frailty syndróm - charakteristika. Paliat Med Liec Boles. 2011;4(2):52-54.
    6. Morley JE. Editorial: Vitamin D: Does the Emperor Have No Clothes? J. Nutr. Health Aging. 2019;23:316-317. doi: 10.1007/s12603-019-1178-x. Go to original source... Go to PubMed...
    7. Müllerová D, a kol. Hygiena, preventivní lékařství a veřejné zdravotníctví. Praha: Karolinum; 2014.
    8. Netz Y. Is there a preferred mode of exercise for cognition enhancement in older age? A narrative review. Front Med. 2019;6:45-57. doi: 10.3389/fmed.2019.00057. Go to original source...
    9. Hegyi L, Krajčík Š. Geriatria pre praktického lekára. 3. vyd. Bratislava: Herba; 2015.
    10. Marcos-Pérez D, Sánchez-Flores M, Proietti S, et al. Low vitamin D levels and frailty status in older adults: a systematic review and meta-analysis. Nutrients. 2020;12(8):228-236. doi: 10.3390/nu12082286. Go to original source...
    11. Zrubáková K, Novysedláková M, Kučíková J. Krehký senior v domácej a ústavnej ošetrovateľskej starostlivosti. Prohuman: odborný internetový časopis - sociálna práca, psychológia, pedagogika, sociálna politika, zdravotníctvo, ošetrovateľstvo [Internet]. 2017. [cit. 2025-06-19]. Dostupné na: http://www.prohuman.sk/osetrovatelstvo/krehky-senior-v-domacej-a-ustavnejosetrovatelskej-starostlivosti.
    12. Zhou J, Huang P, Liu P, et al. Association of vitamin D deficiency and frailty: A systematic review and meta-analysis. Maturitas. 2016 Dec;94:70-76. doi: 10.1016/j.maturitas.2016.09.003. Epub 2016 Sep 13. PMID: 27823748. Go to original source... Go to PubMed...
    13. Gobbens RJJ, Uchmanowicz I. Frailty Viewed From a Nursing Perspective. SAGE Open Nurs. 2023 Jan 5;9:23779608221150598. doi: 10.1177/23779608221150598. PMID: 36636626; PMCID: PMC9829991. Go to original source... Go to PubMed...
    14. Rashidi Pour Fard N, Amirabdollahian F, Haghighatdoost F. Dietary patterns and frailty: a systematic review and meta-analysis. Nutr Rev. 2019 Jul 1;77(7):498-513. doi: 10.1093/nutrit/nuz007. PMID: 31038679. Go to original source... Go to PubMed...
    15. Torné A, Puigoriol E, Zabaleta-Del-Olmo E, et al. Reliability, Validity, and Feasibility of the Frail-VIG Index. Int J Environ Res Public Health. 2021 May 13;18(10):5187. doi: 10.3390/ijerph18105187. PMID: 34068227; PMCID: PMC8153117. Go to original source... Go to PubMed...
    16. Mitnitski AB, Mogilner AJ, Rockwood K. Accumulation of deficits as a proxy measure of aging. ScientificWorld Journal. 2001 Aug 8;1:323-36. doi: 10.1100/tsw.2001.58. PMID: 12806071; PMCID: PMC6084020. Go to original source... Go to PubMed...
    17. Marcos-Pérez D, Sánchez-Flores M, Proietti S, et al. Low Vitamin D Levels and Frailty Status in Older Adults: A Systematic Review and Meta-Analysis. Nutrients. 2020 Jul 30;12(8):2286. doi: 10.3390/nu12082286. PMID: 32751730; PMCID: PMC7469050. Go to original source...
    18. Olexa P, Koval Š. Úskalia a špecifiká manažmentu artériovej hypertenzie v starobe. Geriatria. 2015;21(2):80-91.

    Return to the content


    Medicine for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.