Med. praxi. 2015;12(3)
Med. praxi. 2015;12(3):106-108
Heart failure is a frequent disease with a serious morbidity and mortality. The article summarizes new recommendations for pharmacological therapy for chronic heart failure. The mainstay of treatment is to interfere with neurohumoral activation that plays a crucial role in the pathophysiology of heart failure, in particular with beta blockers and ACE inhibitors; in the case of persistent symptomatology with mineralocorticoid receptor blockers. The results of studies of the angiotensin receptor neprilysin inhibitor appear promising. The recommendations newly include ivabradine.
Med. praxi. 2015;12(3):109-111
The world becomes still smaller and the profile of travellers is changing in time. The objective is to describe a current traveller, possible risks, to summarize the options of the general practitioner, to give simple view on the imported infections, possibilities of their prevention and to evaluate the main risks and necessity of travelling equipment.
Med. praxi. 2015;12(3):112-114
Photoprotection of human skin by means of sunscreens is traditionally centered around the prevention of acute (e.g. sunburn) and chronic (e. g. skin cancer and photoageing) skin damage that may result from exposure to ultraviolet rays (UVB and UVA). Sunscreen products provide efficient photoprotection throughout the entire ultraviolet spectrum.
Med. praxi. 2015;12(3):116-118
The late establishment of the diagnosis of multiple sclerosis results in delay in treatment initiation, affecting the course of the disease, and thus in poorer prognosis. In the case of a false positive diagnosis, in addition to funds being expended inappropriately, the patient is exposed to the risk of adverse drug effects. Particular attention has to be paid to patient history data analysis, proper assessment of clinical evaluation, and realistic interpretation of auxiliary examinations.
Med. praxi. 2015;12(3):121-125
Myasthenia gravis is a chronic autoimmune disease that results in the destruction of functional acetylcholine receptors on the postsynaptic membrane of the neuromuscular junction. Thus, neuromuscular transmission is affected negatively. It is a relatively rare disease with a prevalence of 200/100,000. It is manifested by fluctuating muscle weakness and fatigability. Particularly affected are the extraocular, oropharyngeal, nuchal, girdle, and respiratory muscles. The diagnosis is based on clinical examination, demonstration of pathological antibodies, and electrophysiological testing. Cholinesterase inhibitors are the first-choice therapy;...
Med. praxi. 2015;12(3):126-129
Minimally invasive procedures are essential in the modern treatment of stone disease. In fact, the increasing use of technologically advanced endoscopes reflects the current trend of treating renal pelvis disorders. The development of metaphylaxis in urolithiasis represents an effective causal therapy. Its success largely depends on the appropriate diagnosis of patients and their separation into distinct groups based on the risk factors. The assessment of risk is key to considering further examination and the actual utilization of metaphylaxis.
Med. praxi. 2015;12(3):130-134
The incidence of and mortality from chronic obstructive pulmonary disease (COPD) and cardiovascular disease is high in developed countries. Coronary artery disease is a compelling indication for beta-blockers use in a patient population in whom beta-receptor antagonism is often considered as contraindication. Beta-blockers provide COPD patients with established benefits in the treatment of heart failure and they prolong life after acute myocardial infarction. Cardioselective beta-blockers could save lives and improve quality of life also in appropriately selected asthma bronchiale patients with cardiovascular disease. Because the risk of bronchospasm...
Med. praxi. 2015;12(3):143-145
Pneumococcal endocarditis associated with pneumonia and purulent meningitis is known as Austrian Austrian syndrome. We present a case report of 67-year old patient with coma and left-sided hemiparesis due to purulent meningitis. He subsequently developed pneumonia and sepsis with cerebral absceses. The patient died on the 20th day of illness. Post-mortem examination showed mitral endocarditis. Trans-thoracic echocardiographic examination was negative. Streptococcus pneumoniae serotype 10A was detected from the cerebrospinal fluid. The patient was not vaccinated. Serotype 10A is contained in 23-valent polysaccharide vaccine. Vaccination is the...
Med. praxi. 2015;12(3):148-149
Water intoxication is a relatively rare occurrence in departments of internal medicine. It is a life-threatening condition in which cerebral oedema with neurological symptomatology or even death can occur. The pathophysiology involves hypo-osmolar hyperhydration, with a shift of water into the cells. The condition can have a number of pathological causes, occur as an adverse effect of certain medications, as part of other diseases, due to iatrogenic causes, or as a result of excessive intake of hypo-osmolar fluids in otherwise healthy individuals.
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Med. praxi. 2015;12(3):146
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Med. praxi. 2015;12(3):138-139