Proč mizí z medicíny laskavost?

MUDr. Radkin Honzák, CSc.

Med. praxi. 2024;21(5):263

New trends in asthma treatment

MUDr. Tomáš Balner, doc. MUDr. Jaromír Bystroň, CSc.

Med. praxi. 2024;21(5):270-275 | DOI: 10.36290/med.2024.032

Bronchial asthma is one of the most commonly occurring chronic inflammatory single-molecule diseases worldwide. In recent years, there have been significant advances in asthma research that have contributed to the development of new and more effective therapeutic strategies. The author provides an up-to-date review of the diagnosis, treatment, care, and principles of personalized medicine in asthmatic patients.

Type 1 diabetes mellitus imunopathogenesis - a view for clinical practice

prof. MUDr. Kateřina Štechová, Ph.D.

Med. praxi. 2024;21(5):276-280 | DOI: 10.36290/med.2024.036

Type 1 diabetes mellitus (DM1) is an autoimmune disease in which the insulin-producing β-cells of the pancreas are destroyed by the immune system. In the development of DM1, genetic predisposition plays a role, but also external factors contribute to the breaking of immunological tolerance. The importance of these factors is individual, which is reflected in the clinical heterogeneity of the diabetes clinical onset (different age at manifestation, speed of development of clinical symptoms, etc.). In DM1 patients various immunological abnormalities have been described, however, a key role is still attributed to autoreactive T lymphocytes. A common...

Vaccinations and health preparation before traveling abroad

MUDr. Pavel Slezák

Med. praxi. 2024;21(5):281-284 | DOI: 10.36290/med.2024.041

Traveling is a phenomenon of the times. The general practitioner should be able to give his patient basic advice, and information and direct him to a specialized center for travel medicine. The article is a summary and introduction to the issue. The text can be an outline for pre-travel preparation from anamnesis to routine, mandatory, and recommended vaccinations to the prescription of antimalarial prophylaxis, drugs for the travel first aid kit, and recommendations for protection against insect bites. It also contains links to comprehensive literature and internet resources that are necessary to provide meaningful pre-travel advice.

Maladaptation in the elderly in the context of preventive measures

PhDr. Iveta Ondriová, PhD., PhDr. Terézia Fertaľová, PhD.

Med. praxi. 2024;21(5):285-288 | DOI: 10.36290/med.2024.035

Human aging is a natural, continuous, and irreversible process, during which changes in the organism occur depending on the action of many external and internal factors. The issues of aging and the position of seniors in society are becoming permanently relevant at the economic, psychological, ethical, cultural, health-social, and philosophical levels. This is about the need to promote health purposefully, but also to provide for sick and dependent people, about the need to improve their health status and the possibilities of functioning in society, about offering health programs, and about the effort to extend their active age.

The warts in the general practitioner's office

MUDr. Eliška Dorčáková

Med. praxi. 2024;21(5):289-292 | DOI: 10.36290/med.2024.029

The warts are benign lesions, which occur on the skin, rarely on the mucosa. Children, adolescents, and people with diminished resistance are mostly infected. Human papillomavirus (HPV) is responsible for many lesions. The warts tend to relapse. We differentiate several types of warts - verrucae vulgares, verrucae plantares, verrucae planea juvenilis, verrucae filliformis, and condylomata accuminata.

Critical evaluation of intravenous vitamin C in practice

PharmDr. Marek Lapka, Ph.D.

Med. praxi. 2024;21(5):306-313 | DOI: 10.36290/med.2024.033

Vitamin C is important as a reducing agent and is involved in many biological processes, including collagen and neurotransmitter synthesis. This study aimed to critically review the available information on the potential of intravenous vitamin C (IVC) in oncology and to discuss cases where its use might be indicated. A literature review of available scientific publications focusing on the use of IVC in the treatment of cancer was conducted. Papers from the last two decades were included, including phase I-III trials that evaluated the safety, tolerability, and efficacy of IVC. High-dose IVC has potential as an adjuvant therapy in oncology, particularly...

Cardiovascular risk and combination therapy in practice of 2024

MUDr. Libor Jelínek, Ph.D.

Med. praxi. 2024;21(5):315-319 | DOI: 10.36290/med.2024.048

Cardiovascular diseases are the leading cause of mortality not only in the Czech Republic, but also in most countries of the world, with an ever-increasing prevalence. Arterial hypertension and dyslipidaemia are among the main risk factors for the development of CVD. Treatment is comprised of non-pharmacological measures, mainly changes in diet and increasing the amount of physical activity, as well as pharmacotherapy. Adherence to medication, which can be increased by the use of combination preparations, is a crucial factor in the success of treatment. Early intervention of risk factors will increase the length of life in good health, which is a more...

Léčba gonartrózy III. stupně u polymorbidní pacientky

MUDr. Helena Zedková

Med. praxi. 2024;21(5):320-323 | DOI: 10.36290/med.2024.052

Osteoarthritis is a multifactorial disease that affects a large portion of the population. It is reported that the image of osteoarthritis is visible in X-ray examinations in up to 60% of examined individuals over 65. It is one of the most common causes of morbidity. Osteoarthritis accounts for up to 20% of visits to a general practitioner's office. In younger individuals, it can be a cause of disability. It is a multifactorial degenerative joint disease in which there is a disruption in the renewal of joint cartilage. The joint cartilage loses its luster, softens, and fissures form on its surface. Gradually, the cartilage becomes less resilient and...

Current trends in the use of bacterial lysates

MUDr. Zuzana Humlová, Ph.D.

Med. praxi. 2024;21(5):293-300

Bacterial lysates stimulate the general immunity of the body in a non-specific way. They act on non-specific defense mechanisms, leading to an increase IgA in mucous membranes, phagocytic activity and interferon gamma production. They can also stimulate the production of specific antibodies against the bacterial antigens that make up the preparation. In many clinical trials, oral bacterial lysates have been shown to decrease the risk of recurrent respiratory infections in children and adults and reduce the need for antibiotics.

Drugs with addiction potential

PharmDr. Ivana Tašková, PGDip

Med. praxi. 2024;21(5):302-305 | DOI: 10.36290/med.2024.027

Drug abuse is a serious problem in the Czech Republic, affecting 8-13 % of the population. This phenomenon contributes to significant negative health, social, and economic consequences, including higher hospitalization rates and increased mortality. The most commonly abused and overused drugs are sedatives, hypnotics, and opioid analgesics, which are easily accessible and frequently prescribed medications, but also psychostimulants, antiepileptics, etc. This article focuses on analysing current trends in drug abuse in the Czech Republic, identifying at-risk groups, and managing dependency. Drug abuse is a serious problem among adolescents and young...

Spa care prescriptions: issuing a proposal for spa and rehabilitation care, rules and pitfalls of current legislation

MUDr. Jana Lomozová

Med. praxi. 2024;21(5):324-327 | DOI: 10.36290/med.2024.038

The contribution is intended for doctors to gain a quick orientation in the legislation regarding the prescription of spa medical rehabilitation care for payment from public health insurance and draws attention to the most common shortcomings in the indication of spa care.

The subsequent care for wounds needs to be tailored concerning the patient's capabilities and abilities

Mgr. Hana Vlhová

Med. praxi. 2024;21(5):328-330 | DOI: 10.36290/med.2024.050

The article aims to point to greater interconnectedness and cooperation between health and social care in the field of wound healing. It emphasizes understanding and respecting the mutual effects of individual interventions. This is crucial not only for accelerating and improving wound healing but also for better understanding the context between a doctor's recommendations and a patient's ability to follow them.

Main changes in the new guidelines for the treatment of chronic venous diseases

MUDr. Robert Vlachovský, Ph.D., doc. MUDr. Debora Karetová, CSc.

Med. praxi. 2024;21(5):332-336 | DOI: 10.36290/med.2024.051

The guidelines of the Czech Society of Angiology for the treatment of chronic venous disease (CVD) was published in 2023 as a reflection of international recommendations issued recently. These were mainly the European Society for Vascular Surgery 2022 Clinical Practice Guidelines on the Management of Chronic Venous Disease of the Lower Limbs, published in 2022. The Czech recommendations are in line with these international recommendations, and the text of the multidisciplinary team of Czech authors declared both internationally accepted principles of CVD treatment and reflected local experience and practices. Following the work of the Czech society...

Zaznělo na Sympoziu společnosti Angelini Duben 2024
Digitální závislost, digitální nespavost - víme o nich dost?

MUDr. Zuzana Zafarová

Med. praxi. 2024;21(5):337-342